(18-06-2024, 10:44 AM)Ninja Wrote: Lotas your boobs are amazing great areola size such a nice size, and great nipples. Is it still your opinion not to use Opill I have a 3 moths supply (very cheap$20) but have not started taking it. I have gyno B cup would like to develop further breast tissue am I wrong Opill can develop mid ducts?
Hi Ninja, thank you
, my concern about the Opill was for people who've already had a previous DVT before using the Opill. I'm attaching information about progestins, which the Opill is. I hope the info helps, if not please send me a pm.
Effects of Hormones and Hormone Therapy on Breast Tissue in Transgender Patients: A Concise Review
Estrogen plays a critical role in human breast development, inducing the growth of breast ducts, increasing fat deposition, and promoting breast stromal connective tissue growth. Estrogen upregulates PR expression and induces prolactin, which works in conjunction with progesterone to stimulate breast lobuloalveolar development (12).
Synthetic progestogens (progestins) such as norethisterone, medroxyprogesterone, and lynestrenol, bind to PRs but do not perfectly mimic progesterone and can activate or antagonize other types of steroid hormone receptors (13). Progestins are often prescribed to suppress menses in FTM patients. Studies have shown that these drugs cause a drop in serum levels of SHBG and LH, but significantly increase free testosterone. Estrogen, FSH, and total testosterone, however, do not change significantly (56). As discussed above, progesterone activity on breast tissue includes lobuloalveolar maturation in conjunction with prolactin and, to a much lesser degree than estrogen, ductal development.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252590/