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The Topical Cream Protocol (by NBE Friends)

#21

Hi Katy .... I have to put out a reminder here for everyone that Lotus is still suffering from Leukemia and crushing migraines, so she probably won't be answering individual questions for the time being.

If you have pyramid breasts now early on, this is probably considered normal at this stage. Once you get past Tanner Stage One and into Stage Two, then you can start using Micronized Progesterone Cream. Progesterone helps with side branching.

Be sure to scour the last many years of the Project X thread and the guidelines set forth here in the Topical Protocol thread.

I don't possess anywhere near the scientific knowledge that Lotus does, but I'll help out the best that I can when able.

Best of luck to you.
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#22

Hi all. I guess I'm the one to ask the brain-dead question... Okay, questions... You know, only someone who's brain-dead won't already know the answers...

Does the TCP replace or complement regular NBE or HRT methods, most notably, AA?

Does the TCP get applied once or twice daily?
Does the TCP get cycled off or can it be done every day of the year?
When does RC get applied, every day or alternate? Alternate on day with or without PC?

Can all this TCP stuff be funneled into one thread, not spread out multiples and on "random" pages within the thread?
Can all this be translated into simple English so everyone can easily understand?
Could the TCP be put into some sort or an instruction manual of sorts? Or even, a recipe???

This seems like some groundbreaking information, yet it seems everyone knows how to do this, except me...

I know about Bio-Est, DHEA 50, PC... PC is better as a gel. PC is generally applied every other day. Then RC is great with and without PC.
I did that last month, but only when I cycled off PM on the 3/1 method. I applied RC every day on the last week.

Does E2 replace Bio-Est?

I'm hoping I'll be able to go and go HRT route next year with E2... Should the cream be better? I have no intention to transition.

I'm all over the place, but that's where I am. I'm sorry. In more ways than one...

Lancer
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#23

I'll give my brain dead answers to the brain dead questions. xD lol. Rolleyes


Does the TCP replace or complement regular NBE or HRT methods, most notably, AA
?

It compliments HRT, it can't replace it though. It works the best when there's already a female hormone balance to work with. I'm not sure about AA other than decent T suppression helps EVERYTHING else to do its thing.

Does the TCP get applied once or twice daily?

I do it once a day, evening before sleep but morning and evening could be even a bit better. Keep in mind the stuff takes time to absorb so evening before sleep is better, then sleep with a top so you wont mess up the sheets.

Does the TCP get cycled off or can it be done every day of the year?

I do it daily, the same thing every day, except I take 1-3 days off twice a month to let my skin heal a bit from dermarolling. You can do topicals daily, I don't see any benefit from cycling it other than giving your receptors and skin some time to rest from time to time to avoid dermal fatigue. Which seems like almost a myth, I've never had a problem with that.

When does RC get applied, every day or alternate? Alternate on day with or without PC?

Daily. Or do progesterone and estrogens every other day. I've done stable daily with everything together very successfully, don't see a reason to cycle.

Can all this TCP stuff be funneled into one thread, not spread out multiples and on "random" pages within the thread?


This thread is the place for that, also I've posted a lot in mine too, but as my ideas are what they are, take nothing seriously, except prrof of how well it works.

Can all this be translated into simple English so everyone can easily understand?

I'm here to help with keep-it-simple-stupid explanations, come ask, any time, anywhere. Cool But I will not try to explain every tiny detail as that's not my thing, I know what has proven to work so that's that.

Could the TCP be put into some sort or an instruction manual of sorts? Or even, a recipe???

This would be amazing, some kind of .pdf form ebook of sorts or BN forum wiki or something? I dunno, sounds like a lot of work.


I know about Bio-Est, DHEA 50, PC... PC is better as a gel. PC is generally applied every other day. Then RC is great with and without PC.
I did that last month, but only when I cycled off PM on the 3/1 method. I applied RC every day on the last week.


Every other or just simply daily. I know for a fact that stable dosing works fine. I don't know if cycle would work better? RC I haven't tried yet so can't say anything about it except that the studies seem promising.

Does E2 replace Bio-Est?

Kind of? Except if Bio-Est comes with both estradiol and estriol? But the thing with gel is dosing, none of the creams will have as potent doses unless you use copious amounts of them which doesn't make sense. Same with progesterone, creams are very mild compared to the stuff you get from capsules. Creams are often dosed to 20mg or 40mg, but capsules give 100mg or 200mg. Estrogel does the same thing, no cream you find will give easily 1mg of estradiol in one go unless its fuckton of the stuff.

I'm hoping I'll be able to go and go HRT route next year with E2... Should the cream be better? I have no intention to transition.

No over the counter creams are even close as potent as actual HRT drugs.

I'm all over the place, but that's where I am. I'm sorry. In more ways than one...

Lancer


I hope this helped a bit. Hug
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#24

(29-09-2024, 08:14 AM)DruLactin Wrote:  Wow! That is quite the turnabout from my previous model of reality, but kind of makes sense. It's still a way terrible idea to inject estradiol valerate into your breasts though, right?

Very excited for more, catch ya later.

-Aria

Hi Aria, I wouldn't recommend EV injection. Perhaps future science could explain pinpointing the exact location of epithelial cells within the breast using estradiol injections so as to target estrogen receptors to help initiate growth phase(s) for the folks troubled with extreme loss of breast growth (on a short term basis).  Wink

(29-09-2024, 11:27 PM)Stevenator_ Wrote:  Thank you Lotus for updating the Topical Protocol with research that we can apply to our programs. I appreciate what you do for us very much.

You're welcome Stevenator, and thanks for the help communicating my situation.  Hug

(30-09-2024, 10:38 PM)CM213 Wrote:  Thanks for the updated topical program all in one thread/sub forum. Very informative and interesting. I will def put this to use once I get further along Into my transition.

Glad I can help CM. I like your avatar.  Hug

(22-09-2024, 08:23 AM)wee2er Wrote:  Thanks Lotus yet another fantastic post with all the science behind it, I'm certainly a topical convert  Hug

Thank you wee2er, glad I can help. Hug
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#25

(02-10-2024, 03:00 PM)fem394 Wrote:  Hello! Ive read in Project X that progesterone should not be started until breasts start budding, so is it a bad idea to start a topical program without buds?

Thanks

Hi fem, in (cis-female) puberty breast buds form first before progesterone is stimulated, which happens at stage 4 in the tanner stage after her first menstruation. Letting E2 properly intiate breast buds before adding progesterone helps to improve the essential duct work for proper elongation of the breasts while progesterone develops the essential side branching and improves breast maturation.

Progesterone Is Important for Transgender Women’s Therapy—Applying Evidence for the Benefits of Progesterone in Cis-Women 
Progesterone plus E2 leads to optimal breast maturation and size along with elimination of facial and male pattern body hair, one of the important goals of transgender women is to develop mature and physiological breasts (that are classified as Tanner stage 5) (26). However, currently, the majority seeks breast augmentation surgery (3), because E/E2 plus antiandrogen therapy means the areola stays small (≤2.5 cm, ≤1 inch) and masculine, and breasts remain Tanner stage 3 (27). P4 is necessary for the ductal branching within the breast (and hence, for lactation) (28) and eventual maturation leading to the enlargement of the normal cis-women's areola diameter of ≥3 cm (7). Currently reviewed evidence (29, 30) is inadequate to assess the breast effects of transgender women’s CHT, because breast size, not areolar diameter (the primary difference between Tanner 3 and 5 stages) (26), has so far gone unreported except by one research group (7). The areolar size changes in puberty and during development of ovulatory menstrual cycles, as well as in transgender women on CHT, require further study.
https://academic.oup.com/jcem/article/10...ogin=false
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#26

(05-10-2024, 03:50 PM)katy9 Wrote:  Hi lotus I so much enjoy reading your knowledge on breast growth, I wonder if you could help me,I have tried pm but it makes me bloated, currently on ovarian glandular but I now have pyramid breasts can you suggest which direction to  go appreciate your expertise thank you

Hi katy, thank you.  Hug It's understandable you feel bloated using PM as evidence below details how PM and other phytoestrogens increase triglycerides by 15%... especially using increased amounts of PM. I would suggest looking into adding progesterone cream after breast buds come in. Which hepls to add side branching and mature the overall shape of the breasts snd increased feminization. Look back in this thread covering using progesterone cream. If you need help find PC let me know. Additionally, down the road you can add DHEA. Progesterone Cream dosage starts at a ¼ teaspoon per breast... or enough to cover a thin layer over each breast.

(02-04-2024, 03:53 AM)Lotus Wrote:  PM adds about 500-700 calories per day (from increased triglycerides, per a study I posted in the X-thread).

(06-01-2024, 11:21 PM)Lotus Wrote:  Results:  

After 24 weeks of treatment, 71 women were evaluated. Of the 71 women, 51 randomly received varying doses of Pueraria mirifica and 20 received placebo. Pueraria mirifica and placebo significantly increased triglyceride levels by 15% from baseline levels (P < 0.05). The Pueraria mirifica group showed a significant decrease in bone-specific alkaline phosphatase levels after 24 weeks of treatment compared with the placebo group; from 0.22 ± 0.18 U/L to 0.13 ± 0.01 U/L in the Pueraria mirifica group and from 0.20 ± 0.10 U/L to 0.20 ± 0.14 U/L in the placebo group. Endometrial thickness did not change after treatment in both groups (P > 0.05). No endometrial proliferation or hyperplasia was reported after 24 weeks of treatment in both groups. There were no significant differences in adverse effects on breast tissue, complete blood count, and liver and renal function tests between the Pueraria mirifica and placebo groups in this study.
https://journals.lww.com/menopausejourna...id.22.aspx


Good luck.  Wink
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#27

(06-10-2024, 06:19 PM)Lancer Wrote:  Hi all. I guess I'm the one to ask the brain-dead question... Okay, questions... You know, only someone who's brain-dead won't already know the answers…
 
Lol, I have faith in your ability to learn the science of NBE Lancer. Wink I think you'll need to read this thread a couple of times as I've laid out everything possible covering the TCP. Just As a reminder the dosage for DHEA this:

DHEA dosage, 30 mg, cutaneous application, twice daily + FLU, 7.5 mg, sc, twice daily and (E) DHEA, 30 mg, cutaneous application, twice daily. 
 
Meaning, using DHEA cream at 30mg 2x per day. 

(06-10-2024, 06:19 PM)Lancer Wrote:  Does the TCP replace or complement regular NBE or HRT methods, most notably, AA?

When does RC get applied, every day or alternate? Alternate on day with or without PC?

I would suspend using PM or other phytoestrogens while using the TPC, all three aspects of the TCP utilizes bioidentical hormones… which would interfere with its potential with using PM or phytoestrogens. I'd still use an anti-androgen (e.g. Reishi extract or capsules). Great question. 

(06-10-2024, 06:19 PM)Lancer Wrote:  Can all this TPC stuff be funneled into one thread, not spread out multiples and on "random" pages within the thread?
Can all this be translated into simple English so everyone can easily understand?
Could the TPC be put into some sort or an instruction manual of sorts? Or even a recipe???

This seems like some groundbreaking information, yet it seems everyone knows how to do this, except me…
 
This thread addresses (or encompasses) my latest recommendations for the TCP. This is the one stop thread for TCP. I'll be adding more info and tips (and more discoveries I have along the way). Like advised above, read 2x more (or as many times it takes) to understand the TCP. I have faith in your ability to pick up the TCP protocol, as with any person reading my posts. We don't need a secret decoder ring or to recreate the wheel in understanding what I post. 

(06-10-2024, 06:19 PM)Lancer Wrote:  I know about Bio-Est, DHEA 50, PC... PC is better as a gel. PC is generally applied every other day. Then RC is great with and without PC.

RC does its own thing to further feminize fat tissue. Though the essence of how it works is a bit nuanced. Meaning, the feminizing effects of using RC (or pioglitazone too) takes longer, and you do want to have your E2 levels leaning towards female levels. I'll explain more later. I take RC with a few droppers in water. You can use Bio-Labs cream in place of E2 to start. Eventually, going on HRT (next year) as you stated you'll be in a better place in terms of breast development and feminization. Great questions.  Hug
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#28

Thank you for your help Lotus ,I do have progesterone cream when you say 1/3 of of teaspoon is that applied to the breasts,am I sounding stupid.there is so much to take in on here I learn a little more each day
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#29

(06-10-2024, 11:30 PM)katy9 Wrote:  Thank you for your help Lotus ,I do have progesterone cream when you say 1/3 of of teaspoon is that applied to the breasts,am I sounding stupid.there is so much to take in on here I learn a little more each day

As the saying goes... " no such thing as a stupid question. " Ask a question when you feel comfortable.  Smile
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#30

Thanks Stevenator,there's so many conflicting posts here I'm sure the me berserk are telling us what works for them,and thanks for reminding me about Lotus being unwell,again thanks for your help,love to know how you achieved such wonderful areola,
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