I have been on Bovine ovary, Uterine and Pituitary supplements for a long time and can report that they work fantastically on me, but these clearly have some kind of grey area works or it doesn't kind of thing with them. Some people get nothing, some get something and few get lucky and get amazing changes. I've gotten very lucky as BO in particular has been magic on m. e
I haven't noted any ill effects, not even on highest recommended dose which is said to be optimal. Of course never overdoing any of it like crazy as that would be a waste. The best I can tell, it feels like BO + Uterine + Pit combo feels like its balancing my hormones in a way that conventional HRT can't do on its own. I do not know the science behind this as the science doesn't seem to exist. There's very little studies done on these things.
I've been on these for nearly two years now, took a break and went with BO only for some time and now I'm back with full combination with all three. Works like a charm and no negative health effects so I can say they're quite safe, at least on +2 year timeline of continous use. Likely you have nothing to worry about, just keep doses within moderation.