[Lotus]

    Don't forget about the endocrine system!

[myboobs]

Crumbs !! Think I will have to read that over a few times to memorise and remeber what I read !!
Plebs like me are like upturned vessel and trying to fill that is hard work
Thanks again for brill post

[Carys]

This is incredible info! Thanks for bringing it all in one place!

[Lotus]

Instead of having 3-4 threads talking about male NBE needs I'm condensing all of them into one, making it streamlined for ease of use and reference. Big thanks to our friend jacp!

5 hormones needed for breast growth:

1) Estrogen- are a group of compounds named for their importance in both menstrual and estrous reproductive cycles. They are the primary female sex hormones. Natural estrogens are steroid hormones, while some synthetic ones are non-steroidal.

2) Progesterone -Progesterone is produced in the ovaries (by the corpus luteum), the adrenal glands (near the kidney), and, during pregnancy, in the placenta. Progesterone is also stored in adipose (fat) tissue. but it can also be increased through the use of natural progesterone cream, which is derived from soy or wild yam. PC can be useful for bio-males

3) Prolactin- Prolactin (PRL), also known as lactotrope, is a protein that in humans is probably best known for its role in enabling female mammals to produce milk, increases fat stores in the breasts. Massaging breasts stimulates prolactin.

4) Growth Hormone-also known as somatotropin or somatropin, is a peptide hormone that stimulates growth, cell reproduction and regeneration in humans and other animals. It is a type of mitogen which is specific only to certain kinds of cells. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland.

5) Testosterone -is converted into estrogen by a process called aromatase. The aromatase process takes place in the body’s fat cells, which create a special substance called an aromatase enzyme which converts excess testosterone into estrogen.

Definitions-

Aromatase: An enzyme involved in the production of estrogen that acts by catalyzing the conversion of testosterone (an androgen) to estradiol (an estrogen).


Aromatase inhibitors(AIs) are a class of drugs used in the treatment of breast cancer and ovarian cancer in postmenopausal women. They may also be used off-label to treat or prevent gynaecomastia in men.
Aromatase is the enzyme that synthesizes estrogen. As breast and ovarian cancers require estrogen to grow, AIs are taken to either block the production of estrogen or block the action of estrogen on receptors.

Pro-Hormones -refers to a committed intra-glandular precursor of a hormone, usually having minimal hormonal effect by itself. The term has been used in medical science since the middle of the 20th century. Though not hormones themselves, prohormones amplify the effects of existing hormones. Examples of natural, human prohormones include proinsulin and pro-opiomelanocortin.

Potentiator-is a drug, herb, or chemical that intensifies the effects of a

The Three E's, (E1), (E2), (E3)
(E1)-Estrone (E1, and also oestrone) is an estrogenic hormone secreted by the ovary as well as adipose tissue,Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily during pregnancy. (E2),Estradiol is about 10 times as potent as estrone and about 80 times as potent as estriol in its estrogenic effect (E3) Estriol is only produced in significant amounts during pregnancy as it is made by the placenta.

Androgens also called androgenic hormone or testoid, is the generic term for any natural or synthetic compound, usually a steroid hormone, that stimulates or controls the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.

Anti-androgens,-or androgen antagonists, first discovered in the 1960s, prevent androgens from expressing their biological effects on responsive tissues.Antiandrogens alter the androgen pathway by blocking the appropriate receptors, competing for binding sites on the cell's surface, or affecting androgen production.

Estrogen receptors -are a group of proteins found inside cells. They are receptors that are activated by the hormone estrogen (17β-estradiol).

Sex hormone-binding globulin-Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to sex hormones, to be specific, androgens and estrogens. Other steroid hormones such as progesterone, cortisol, and other corticosteroids are bound by transcortin.


Free testosterone-is a term that refers to the amount of testosterone in the bloodstream, usually tested in males with certain medical conditions. According to the American Association for Clinical Chemistry (AACC), free testosterone only accounts for 1-4 percent of the testosterone in a typical male's bloodstream.

5-ar - 5 alpha reductase - converts testosterone into dht.

Cyp 19 - Aromatase gene - You can find articles on herbs that increase aromatase via this search term

DHT- Dihydrotestosterone - The most potent androgen, destroys fat, and masculinizes.

DHEA - Dehydroepiandrosterone - Building block hormone for everything else.

Steroidogenesis -is the biological process by which steroids are generated from cholesterol and transformed into other steroids.[The pathways of steroidogenesis differ between different species – as an example the pathways of human steroidogenesis are shown in this figure below: The major classes of steroid hormones and some prominent members of the human steroidogenesis are:

See attached file for the hormonal pathway-

Estrogenic Herbs:
Pueraria Mirifica - Awesome for breast growth.
Red Clover - Minor aromatase inhibitor, but highly estrogenic. Binds some to alpha estrogen receptors(boob growth receptor).
Hops - Not as estrogenic as PM or red clover, but activates alpha estrogen receptors which stimulate breast growth.

Pro-hormone's:
DHEA - The direct building block of other hormones
Fish oil - provides plenty of good fats and nutrients for hormone production.
FATS/Protein - Go to town. The more fats you take in the more your body has for hormone production. Cholesterol is a direct building block for all other hormones. No more 'light' anything. Whole and saturated fats.
Bovine ovaries - Also estrogenic, and I think pro-aromatase, as well as 5-AR inhibiting.

Pro-Aromatase:
Peony Root - Estrogenic, blocks 5ar and pro-aromatase - Strong.
genistein - Estrogenic and pro-aromatase
Licorice - Anti-androgenic and activates alpha and beta estrogen receptors and blocks 5-ar - Strong, but take in moderation! Link with more info.

Potentiators:
Dandelion root - Good for detoxing the liver, and upregulates estrogen receptors so your body uses the estrogen you are putting in.
Nettle Root - Binds to SHBG (hormone that binds to excess hormones decreasing hormone levels), and decreases 5ar and aromatase. Taking this tends to increase estrogen and testosterone. Would need to be taken with a pro-aromatase, and maybe estrogen.
PABA - Decreases breakdown of estrogen in your body so you have more free estrogen.
Gaba - Increases growth hormone
Grape fruit - Slow the breakdown of estrogen
Deer velvet - Increases growth hormone

Theory:
Breasts grow with a mixture of estrogen and growth hormone. This happens naturally, because your body reacts to estrogens by releasing growth hormone, but I'm thinking you could add supplement to this. Or that estrogen acts as the growth hormone. Bovine ovaries causes a whole cascade of estrogens and growth hormone release, which is why it seems like it is so effective.

So a solid cycle could look like:
1 estrogenic herb
1 pro-hormone
1 pro-aromatase
1 potentiator (vitamins/minerals, etc)

Don't forget about the endocrine system!

http://www.breastnexus.com/attachment.php?aid=5244




Please add/subtract to the list as needed-

Reference : http://wikipedia.org/wiki/Wikipedia

[Samantha Rogers]

Really nice synopsis, Lotus.
But it troubles me that the list put together by jacp114 ignores PG. I am more and more coming to believe PG is very important to include in our breast building cocktail.

[Lisa Lou]

Thanks for consolidating the information LA, this will be a fabulous resource that can be continually updated as additional information is gathered and different herbs/methodologies are tested. For those that come behind us, at least they may be spare the hours of researching the site and the web to get basic information. Very sisterly of you!

Samantha, I tend to agree, and will join you in exploring. After reading up on the whole theory of imitating the female cycle, I used PC for 4-5 days once a month.

Question, LA, this is a great idea and I don't want to f-it up. If for example I research and find information on PC, should I post it in a separate thread and defer to you to add to this if it has merit? My first thought is this will probably not be a heavily traffic'd thread, and you will want to reserve the right to edit it so it doesn't get unwieldy.

Just my 4 a.m. $.02

LL

[AmandaBust]

Wow Lotus, you have been busy! thank you for taking the time to do all of the research and for sharing it with us!

I would like to see massage and a little fat binding added to any program as the potential for added fat in the breasts are ultimately what most of us are looking for.

Funny how Fat, in the right places, can make all the difference!

-A

[Lotus]

I added SBGH and FREE Testosterone, I would think this will continue to evolve, or devolve!

If a more tech savvy can person can make an add-on list sheet that would be greatly appreciated

But it troubles me that the list put together by jacp114 ignores PG. I am more and more coming to believe PC is very important to include in our breast building cocktail.

Great, I used it early into my program, please post what you have on it!

If for example I research and find information on PC, should I post it in a separate thread and defer to you to add to this if it has merit?

Please post whatever you think is helpful!

I would like to see massage and a little fat binding added to any program as the potential for added fat in the breasts are ultimately what most of us are looking for.

Please post your findings if you wish!

[Lotus]

My first thought is this will probably not be a heavily traffic'd thread, and you will want to reserve the right to edit it so it doesn't get unwieldy.

Captain!, I'm sure I'll keep it busy! , but it would be awfully boring if it was just me!

[Lotus]

Common acronyms-
BO: Bovine ovary
EPO: Evening primrose oil
FG: Fenugreek
GR: Goat's Rue
MSM: Methyl sulfonyl methane
NBE: Natural breast enhancement
BB: Bountiful Breast
SP: Saw Palmetto
PM: Pueraria Mirifica
NR: Nettle Root
DIM: Diindolylmethane
PC: Progesterone
T: Testosterone
PRL: Prolactin
AF: Auntie Flow
E: Estrogen
SHBG: Sex Hormone-Binding Globulin
GH: Growth Hormone
AI: Aromatase inhibitor
AA: Anti-Androgen
ER: Estrogen Receptors
5-ar: 5 alpha reductase - converts testosterone into dht.
DHT: Dihydrotestosterone
DHEA: Dehydroepiandrosterone
RC: Red Clover
PSO: Pumpkin Seed Oil
WY: Wild Yam
BA: Breast Active
BC (coho): Black or Blue Cohosh
BT: Blessed Thistle
LT: L-Tyrosine
MT: Milk Thistle
TF: Transfemme
SNR: Stinging Nettle Root (or NR - Nettle Root)

PO: porcine ovary, SO: Sheep Ovary