[BigDee]

Well, as a matter of fact We have a lot of Shakespeare (and tights...hee hee) in our past. And I was very cute in those tights, I'll have you know! LOL

shakspeare in tights with boobies !! now that is something to see

Did You Know?
The first woman to appear in a Shakespeare play did so in 1660 – 44 years after Shakespeare’s death.
http://www.theatreunbound.com/know/facts...eare.shtml

I thought I remembered that the actors at the time were all male.

BigDave

[BigDee]

Looking good Lotus. Some day I may get to where you are.

BigDave

[BigDee]

I once wore a pair of short cut-off jeans to a bar (this was back in my early 20's), the men didn't say anything, but the women sure did!

BigDave

[Lotus]

Thanks BigD, I'll bet those girls were envious! someday I might be as creative as you! btw, I'm impressed with your program!

[BigDee]

Thanks BigD, I'll bet those girls were envious! someday I might be as creative as you! btw, I'm impressed with your program!

Hi Lotus,

That was over 35 years ago. I don't know how envious they were, muscular, slightly hairy and scars. At the time I could leg press almost 900 lbs.

My program right now is just PM, massage and occasional noogling.
My original program was chosen because of what I read in the Green Pharmacy by James A. Duke, PhD and here, and what was available at the local grocery stores and Walmart.

BigDave

[Epi]

Excellent work on this guide! It has information that I wasn't even aware of and will definitely have to be added to my routine when I have a job! Do you have any dosage recommendations? I may have missed them, sorry if I did! They are all definitely topics worth researching, thanks!

To illustrate Estrogen Receptors!

Estrogen receptors
Estrogen receptors are a group of proteins found inside cells. They are receptors that are activated by the hormone estrogen (17β-estradiol).[1] Two classes of estrogen receptor exist: ER, which is a member of the nuclear hormone family of intracellular receptors, and GPR30, which is a member of the rhodopsin-like family of G protein-coupled receptors. This article refers to the former (ER).
Once activated by estrogen, the ER is able to translocate into the nucleus and bind to DNA to regulate the activity of different genes (i.e. it is a DNA-binding transcription factor). However, it also has additional functions independent of DNA binding.[2]


...

Distribution
Both ERs are widely expressed in different tissue types, however there are some notable differences in their expression patterns:[7]

The ERα is found in endometrium, breast cancer cells, ovarian stromal cells, and the hypothalamus.[8] In males, ERα protein is found in the epithelium of the efferent ducts.[9]

The expression of the ERβ protein has been documented in ovarian granulosa cells, kidney, brain, bone, heart,[10] lungs, intestinal mucosa, prostate, and endothelial cells.

The ERs are regarded to be cytoplasmic receptors in their unliganded state, but visualization research has shown that a fraction of the ERs resides in the nucleus.[11] The "ERα" primary transcript gives rise to several alternatively spliced variants of unknown function.[12]

TMI, but I'm missing part of my penis and all of the precious estrogen receptors that were part of that. Will having less estrogen receptors mean less results and/or slower results? Is there a way to create new estrogen receptors to make up for the ones that are gone? Are there any benefits from having less, like less of a risk of getting estrogen-induced cancer? Will the others just absorb more to make up for the ones that are gone? If that happens, won't the others die faster because they have to work harder? Sorry about all of the questions, I'm just new to this and it's as if the loss that I am trying to compensate for is only further-inhibiting my plans for compensating for it, like it's counter-productive, like someone destroyed something that was passed down in your family for one-hundred generations, and if that isn't bad enough as it is, their ghost is living on and haunting you and preventing you from doing something to make up for damage that you didn't even ask to happen. OK, it's a rant at this point. T_T But happy face, there isn't anything to be concerned about. Please though, answers to those questions would be appreciated. Thank you.

[The First Aria]

TMI, but I'm missing part of my penis and all of the precious estrogen receptors that were part of that. Will having less estrogen receptors mean less results and/or slower results? Is there a way to create new estrogen receptors to make up for the ones that are gone? Are there any benefits from having less, like less of a risk of getting estrogen-induced cancer? Will the others just absorb more to make up for the ones that are gone? If that happens, won't the others die faster because they have to work harder? Sorry about all of the questions, I'm just new to this and it's as if the loss that I am trying to compensate for is only further-inhibiting my plans for compensating for it, like it's counter-productive, like someone destroyed something that was passed down in your family for one-hundred generations, and if that isn't bad enough as it is, their ghost is living on and haunting you and preventing you from doing something to make up for damage that you didn't even ask to happen. OK, it's a rant at this point. T_T But happy face, there isn't anything to be concerned about. Please though, answers to those questions would be appreciated. Thank you.

If that were true, then true hermaphrodites would never develop secondary characteristics. For example... facial or body hair. IMO, it would be less work, for whichever hormones you are dealing with.

[Lotus]

Excellent work on this guide! It has information that I wasn't even aware of and will definitely have to be added to my routine when I have a job! Do you have any dosage recommendations?


TMI, but I'm missing part of my penis and all of the precious estrogen receptors that were part of that. Will having less estrogen receptors mean less results and/or slower results? Is there a way to create new estrogen receptors to make up for the ones that are gone? Are there any benefits from having less, like less of a risk of getting estrogen-induced cancer? Will the others just absorb more to make up for the ones that are gone? If that happens, won't the others die faster because they have to work harder? Sorry about all of the questions, I'm just new to this and it's as if the loss that I am trying to compensate for is only further-inhibiting my plans for compensating for it, like it's counter-productive

I'm a little confused, you're adding health related disclosures as you go, kinda of makes it difficult to give advice when you get tidbits of info. I'll provide additional info but I can't give dosing advice at this point, I will suggest you dig deeper and fill your brain as much as you can on NBE.

PM tricks the brain into thinking its real (E2), PM attaches to the receptors and occupies, binds and stimulates them as if it were real estrogen without all the cancer related effects of real estrogen. The attached file is the receptor sites, but it's much more than that, each receptor reacts differently, and some not so friendly. I suggest you need to research the whole process.
   

[Lotus]

    This is how/what PM targets:



Btw, here's a great site that explains the receptors!
http://www.pdg.cnb.uam.es/cursos/Barcelo...Intro.html

[Epi]

Thank you for the diagrams and links, will be sure to do some additional reading! Does the number of receptors in the body make a difference? Will my results with less receptors be equal to how they would have been had I had all estrogen receptors? Thank you!