Your last post seems to contain really important information if it is reliable. Where was it originally posted, since it seems to me that it should be referenced in the blog? What I would still like to know is the actual timing of the metabolism of PM. Assuming it is taken orally, it must take a certain time for it to reach the liver and for the estrogenic components to rise and then fall in the bloodstream, and to bind to the estrogen receptors that can use them. What is the duration of this last process and how often does the bound estrogen need to be replaced? I have never seen any hard data on even the half life of the PM estrogens, beyond a guesstimate of two or three hours, but I suspect that the receptor binding and assimilation phase may be longer - there certainly seems to be a continuing effect for a couple of days when PM is stopped. I may have misunderstood these mechanisms, bur some guidance as to the sequence of events and their timing would be useful in devising dosage routines.
To get back to your main query, your objectives are very similar to my own, but I don`t think that I can help you very much, because having already lost normal male function I don`t really have to bother about preserving it