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Ok .... Quick question.
Has anyone come across the known usefull life expectancy of these patches ?
" 5 cm2 patch containing 0.78 mg estradiol (as hemihydrate) with a release rate of 50 micrograms estradiol per 24 hours. "
My pharmacist says 1 twice a week, as in one for 3 days then one for 4 days ... So I'm thinking why not just say 3 1/2 days ? Or if the patch just delivers less after 3 days, then leave it on for 4 1/2 days and get a little more out of it ? ( ie: two patchs for the extra 24 hrs )
Thoughts and comments appreciated.
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I did find a PDF study that seems to indicate the patch administers 50mg for 84 hrs.
It also mentions the 1/2 life of estrodol is only an hour. and blood testa show normal after 24 hrs of patch removal.
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Janet, I was doing two 0.1 mg Climara before switching to injections. The doctors had me changing them as you say but I started changing every 4 days. The manufacturer stated for women to place one patch every seven days. So I think there is probably enough strength in those to last beyond four day rotations with no problem. And, I have breast buds and growth to prove it. So it definitely worked with me. On the shots I only take one every two weeks. Go figure.
KellyT[/align]
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(29-04-2016, 01:02 AM)KellyT Wrote: Janet, I was doing two 0.1 mg Climara before switching to injections. The doctors had me changing them as you say but I started changing every 4 days. The manufacturer stated for women to place one patch every seven days. So I think there is probably enough strength in those to last beyond four day rotations with no problem. And, I have breast buds and growth to prove it. So it definitely worked with me. On the shots I only take one every two weeks. Go figure.
KellyT[/align]
I ended up leaving the patches on and overlapping by 32 hrs.( extending from 3.5 days to 5 days ). I get my blood work ( again ) next week, and see the phsycologist again in two weeks. To be honest, I hope I can persuade her to up the estrogen, on only .78 I feel I was getting some better growth results from PM ( 2500mg ) and WP.
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(29-04-2016, 02:44 AM)jannet.duff Wrote: (29-04-2016, 01:02 AM)KellyT Wrote: Janet, I was doing two 0.1 mg Climara before switching to injections. The doctors had me changing them as you say but I started changing every 4 days. The manufacturer stated for women to place one patch every seven days. So I think there is probably enough strength in those to last beyond four day rotations with no problem. And, I have breast buds and growth to prove it. So it definitely worked with me. On the shots I only take one every two weeks. Go figure.
KellyT[/align]
I ended up leaving the patches on and overlapping by 32 hrs.( extending from 3.5 days to 5 days ). I get my blood work ( again ) next week, and see the phsycologist again in two weeks. To be honest, I hope I can persuade her to up the estrogen, on only .78 I feel I was getting some better growth results from PM ( 2500mg ) and WP.
Felt like that too when making the switch. Maybe it takes a while for the body to adapt from miroestrol to estradiol? Your bloodtests will tell you more.
x
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01-05-2016, 06:01 PM
(This post was last modified: 01-05-2016, 06:02 PM by
jannet.duff.)
Well, I'm not happy at all.
After being off herbs for almost 3 weeks, ( just on this low synthetic ). Mr happy woke me up this morning, looking around like a viper looking to strike out. This is not good, it tells me my "T" is creeping back up.
My bloodwork is on Tuesday, after that I think I'll add some Reishi back into the mix.
Lotus, do you have any notes on what PM is equivalent too in synthetics ? IE: what would 2500mg of PM equate too in synthetic estrogen.
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(01-05-2016, 06:01 PM)jannet.duff Wrote: Well, I'm not happy at all.
After being off herbs for almost 3 weeks, ( just on this low synthetic ). Mr happy woke me up this morning, looking around like a viper looking to strike out. This is not good, it tells me my "T" is creeping back up.
My bloodwork is on Tuesday, after that I think I'll add some Reishi back into the mix.
Lotus, do you have any notes on what PM is equivalent too in synthetics ? IE: what would 2500mg of PM equate too in synthetic estrogen.
Hi Jannet, if farm cultivated PM is harvested for 8-10 years (verified?) and has artifact miroestrol/dexymiroestrol, it's roughy .25 mg per 500-1000mg. 2500mg PM will equate to .75mg of E2 (@ pharma 1-2mg of E2). This is the problem of PM though, it's unlikely the PM has any verifiable miro/dexymiroestrol.
If a supplier stepped up to the plate with a current COA of PM that proves miro/dexymiroestrol content?, well then, it's a whole new program for that supplier.
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05-05-2016, 12:33 AM
(This post was last modified: 05-05-2016, 12:36 AM by
jannet.duff.)
Well, my blood work just got back.
I'll say I'm not happy with the results.
2 months ago on herbs, my bound "T" was 10.6 nmol/L. ( nom 8.4-28.8 )
Free "T" was 41 pmol/L. ( nom 179-475 )
This week. Free "T" was 174 pmol/L ( nom 179-475 )
"Estradiol " was only at 160 pmol/L ( nom <150 ).
Needless to say, the Dr and I are going to have a discussion in our meeting next week. In the mean time I'm leaving all patches on for a full 7 days, they will only be coming off when they get changed. I am also contemplating making another WP purchase.
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It's not horrible, but I'd be pissed too. What's your SHBG?, I'd like to calculate the freeT and bioT %'s.
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(05-05-2016, 01:41 AM)Lotus Wrote: It's not horrible, but I'd be pissed too. What's your SHBG?, I'd like to calculate the freeT and bioT %'s.
The SHBG was not indicated ?
