Sorry I disagree. You're using a biological female as an example. One other thing, was she a sedate person, sitting alot? Like at a desk? That alone makes blood pool in the lower legs and increases clotting chances even without an extra shot of estrogen. I am currently on
8mgs of Estrodial tabs, sublingual, with Saw Palmetto (750mg) as an anti androgen and have been on them for almost 5 months. The half life of estrodial is around 7 hours. That's the point where 1/2 of the dose is eliminated with the remaining dose slowly being eliminated thruout the evening, with the blood level falling off as well. I take my tabs early in the morning, and then late in the evening I use a PM breast cream, Bella Cream, and then a phyto estrogen 500mg.
As far as heading off clots, take an aspirin a day. A single aspirin has been proven to drastically reduce chances of clotting.
http://patient.info/health/aspirin-and-o...-medicines I also Noogle for an hour in the mornings and another hour thru the day. The split treatment, 15on/7off. I'm almost to big now for the cups I currently have and will be buying a larger set soon. I'm using the AtoB ones currently. One thing people don't know is, estrogen is destroyed by caffeine. So I avoid taking my tabs for several hours after having morning coffee. I'm sure the same holds true for any caffeinated drinks.
Estrogen therapy for biological females is very different than for MTF. The risk factors are also quite different. One thing I noticed during my first therapy when I was younger, was the calming effect of the estrogen. I was using Estrodial Cypionate with 4mgs of tabs. But after several months I noticed my thinking, thought process, was changing and I was getting to where I didn't really care for my wife lol. I would catch myself crying during a touching scene in a movie and was actually thinking more like a woman I "think". I'm sure if I would have continued, it wouldn't have been long before we divorced. And she was supportive of this lol.
One thing I am missing in my current routine is Estrodial Cypionate injectable. That's why I use the phyto estrogen to compensate, without raising my estrodial dose, 8mgs is the max imo. But when I do get access to some, still looking, I will discontinue them and cut back to 6mgs daily.