(23-01-2018, 05:00 PM)VergeOfDiscovery Wrote: Smoking, estradiol metabolism and hormone replacement therapy
it has been proven that, depending on the type, duration and intensity of nicotine consumption, smoking can reduce or completely cancel the efficacy of orally administered estrogens.
But there's this...
who continue to smoke despite all warnings should therefore only be treated via the transdermal route
https://www.ncbi.nlm.nih.gov/pubmed/15638743
Nicotine Blocks Brain Estrogen Synthase (Aromatase)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904480/
Cigarette smoking and nicotine have complex effects on human physiology and behavior, including some effects similar to those elicited by inhibition of aromatase, the last enzyme in estrogen biosynthesis
(23-01-2018, 05:38 PM)Jennipher Wrote:(23-01-2018, 05:00 PM)VergeOfDiscovery Wrote: Smoking, estradiol metabolism and hormone replacement therapy
it has been proven that, depending on the type, duration and intensity of nicotine consumption, smoking can reduce or completely cancel the efficacy of orally administered estrogens.
But there's this...
who continue to smoke despite all warnings should therefore only be treated via the transdermal route
https://www.ncbi.nlm.nih.gov/pubmed/15638743
Nicotine Blocks Brain Estrogen Synthase (Aromatase)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904480/
Cigarette smoking and nicotine have complex effects on human physiology and behavior, including some effects similar to those elicited by inhibition of aromatase, the last enzyme in estrogen biosynthesis
Thanks VOD! Guess I’ll try patch along with NBE, and see. I’ve cut back significantly, so I’m hoping 2-3 weeks will suffice and then I will rely on gum if/when necessary.
Cheers!
Jenn