Hi there. I just finished 6 months on PM. While the results have been fantastic, I’m struggling with leg cramps — mostly in the upper leg (quads and hamstrings). Has anyone else experienced this? I really want to continue on, but I worry this is a negative side effect. 

Randi

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You need to re-evaluate taking PM! Those cramps might be a DVT symptom!

I had this happen while on PM, back then I also smoked and I have naturally thick blood. That was a major scare as I'm not planning dying to a blood clot. How painful it is? Mine got so bad as to keep me awake at night, major scare. Stopping PM for a while and or going on lower dose helped. Obviously switching to conventional HRT assisted with all the hormone magic we talk about here solved this issue.

You can try lower your dose or take a break and see if the cramps go away. This is something you don't want to take a risk about, so be careful.

You need to re-evaluate taking PM! Those cramps might be a DVT symptom!

I had this happen while on PM, back then I also smoked and I have naturally thick blood. That was a major scare as I'm not planning dying to a blood clot. How painful it is? Mine got so bad as to keep me awake at night, major scare. Stopping PM for a while and or going on lower dose helped. Obviously switching to conventional HRT assisted with all the hormone magic we talk about here solved this issue.

You can try lower your dose or take a break and see if the cramps go away. This is something you don't want to take a risk about, so be careful.

Thanks for responding. I appreciate the advice. I actually thought about a short pause to see if things improve. I’m on 1000 mg a day, which seems to work well for me. I know I had some issues after switching to this brand due to how potent it was. I had a great deal of elevated anxiety. So perhaps it’s related. I had a round of blood work done last month and there were no elevated signs that concerned the doctor. We talked about switching to HRT, but I’m just not ready for that. I know that’ll change in the future. 

Overall, I’ve been very happy with PM, and I’ve had many fem changes.

I was taking PM and for sometime along with other things my boobs started to grow and I could feel breast buds starting. Then for some reason I started getting stomach cramps when I took PM. Anrrowed it down to the PM off for a eeek and started PM after a week stomach cramps --had to stop and switch to PM cream moon my boobs. I would stop the PM for awhile and. then start see if you get leg cramps.  Oh and your picture looks lovely nice boobs on your very fit small frame

Hi Randi

Cramps while on PM are common (it happens to me all the time while on PM) and the reason for them is the lower testosterone in your body. To put it bluntly, you are weaker when taking PM. It's the same effect that takes away erections and that makes you less snappy. They probably are not caused by blood cloths, which will hurt a lot more than a cramp.
What I noticed is that PM acts better when all the side effects have come into play. The cramps, lack of sex drive etc... are all signs that your body is functioning in a more feminine way, and that the effects of estrogen in your body are maximised. My bad advice is: if you can pull through, pull through. Once your body adapts to the lower T and higher E, the feminization process will likely speed up and be even more effective.

Great picture, by the way. Your breasts look amazing, particularly for just 6 months!

Hi Randi

Cramps while on PM are common (it happens to me all the time while on PM) and the reason for them is the lower testosterone in your body. To put it bluntly, you are weaker when taking PM. It's the same effect that takes away erections and that makes you less snappy. They probably are not caused by blood cloths, which will hurt a lot more than a cramp.
What I noticed is that PM acts better when all the side effects have come into play. The cramps, lack of sex drive etc... are all signs that your body is functioning in a more feminine way, and that the effects of estrogen in your body are maximised. My bad advice is: if you can pull through, pull through. Once your body adapts to the lower T and higher E, the feminization process will likely speed up and be even more effective.

Great picture, by the way. Your breasts look amazing, particularly for just 6 months!

I read cramping may be a side effect even on HRT. Therefore, it’s not much of a surprise that PM would have similar symptoms. I’m not so concerned with clots, the symptoms are significantly different. But I was curious if others have had similar experiences and what they did to prevent it or at least minimize it. I’m thinking of lowering the dose over the next few weeks to see if that changes anything. I never thought lower testosterone levels may have some negative impacts. My blood results did confirm a decline in T levels. My body is definitely changing in a more feminine way. Legs are noticeably smaller and my butt has gained some fat. The weight gain was a surprise considering my activity level, but it’s still manageable. 

Thank you. My boobs are starting to fill nicely into an A cup. Though a push-up bra makes them appear as they’re bigger   I really love these fem changes.

I was taking PM and for sometime along with other things my boobs started to grow and I could feel breast buds starting. Then for some reason I started getting stomach cramps when I took PM. Anrrowed it down to the PM off for a eeek and started PM after a week stomach cramps --had to stop and switch to PM cream moon my boobs. I would stop the PM for awhile and. then start see if you get leg cramps.  Oh and your picture looks lovely nice boobs on your very fit small frame

thank you so much. I appreciate the compliment and insight. I’m going to reduce the dosage over the next month to see if anything changes. I really don’t want to stop but I’m okay to slow things down. I love the fem changes. And I feel more confident and calmer about life. 

I used to get extreme leg cramps in my calves when I was taking PM. I haven't had any since I switched to HRT. As said above, they're not something to ignore.

I've never heard of leg cramps being a thing with HRT, at least not with bioidentical stuff we use today. It could be DVT symptom, especially when taking phytoestrogens or synthetic estrogen or progestins or taking estrogen orally. Lowering dosage or taking a break would be the smartest move to consider.

Hi Randi

Cramps while on PM are common (it happens to me all the time while on PM) and the reason for them is the lower testosterone in your body. To put it bluntly, you are weaker when taking PM. It's the same effect that takes away erections and that makes you less snappy. They probably are not caused by blood cloths, which will hurt a lot more than a cramp.
What I noticed is that PM acts better when all the side effects have come into play. The cramps, lack of sex drive etc... are all signs that your body is functioning in a more feminine way, and that the effects of estrogen in your body are maximised. My bad advice is: if you can pull through, pull through. Once your body adapts to the lower T and higher E, the feminization process will likely speed up and be even more effective.

Great picture, by the way. Your breasts look amazing, particularly for just 6 months!

I'm taking PM and I've noticed the same thing. I usually only take one PM capsule a day with RR sometimes two. I also use PM cream on my breasts too. If I get a leg cramp it's usually in the morning when I stretch in bed before I get up along with no morning wood. I only got breast buds and some development when these all came into play as you mention. I do worry about getting a DVT though and in the back of my mind I do wonder if this is something to worry about.

I think DiDi is pretty smart and has good advice. I've been doing this now for over three years and still not sure where I'm at T and E wise without tests.